Testing the Protective Properties of the Extract of Monarda Fistulosa Var. Menthifolia L. Regarding the Effect of the Anticancer Drug Etoposide on the Example of Drosophila Melanogaster

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Testing the Protective Properties of the Extract of Monarda Fistulosa Var. Menthifolia L. Regarding the Effect of the Anticancer Drug Etoposide on the Example of Drosophila Melanogaster. / Antosyuk, O. N.; Bolotnik, E. V.; Obvitsev, D. V.
в: Journal of Herbs, Spices & Medicinal Plants, Том 29, № 3, 2023, стр. 308-317.

Результаты исследований: Вклад в журнал › Статья › Рецензирование

BibTeX

@article{d350d2da157647599f662b7e49d60100,

title = "Testing the Protective Properties of the Extract of Monarda Fistulosa Var. Menthifolia L. Regarding the Effect of the Anticancer Drug Etoposide on the Example of Drosophila Melanogaster",

abstract = "The protective properties of the extract of Monarda fistulosa var. menthifolia were tested when used together with the antitumor drug etoposide on Drosophila melanogaster. 1%, 10% extracts of M. fistulosa var. menthifolia were tested, separately and together with etoposide at 800 µg kg−1 of nutrient medium. The genotoxic effect was determined using the SMART method. Cytotoxicity was determined by assessing regulated cell death (RCD). While the extract of M. fistulosa var. menthifolia at 1% (20 mg mL−1) did not show genotoxicity, and had antigenotoxicity, reducing the genetic activity of the anticancer drug etoposide, at 10% (200 mg mL−1) it showed geno- and cytotoxicity. {\textcopyright} 2023 Taylor & Francis Group, LLC.v",

author = "Antosyuk, {O. N.} and Bolotnik, {E. V.} and Obvitsev, {D. V.}",

note = "The research funding from the Ministry of Science and Higher Education of the Russian Federation (Ural Federal University Program of Development within the Priority-2030 Program) is gratefully acknowledged.",

year = "2023",

doi = "10.1080/10496475.2023.2180698",

language = "English",

volume = "29",

pages = "308--317",

journal = "Journal of Herbs, Spices & Medicinal Plants",

issn = "1049-6475",

publisher = "Taylor and Francis Ltd.",

number = "3",

}

RIS

TY - JOUR

T1 - Testing the Protective Properties of the Extract of Monarda Fistulosa Var. Menthifolia L. Regarding the Effect of the Anticancer Drug Etoposide on the Example of Drosophila Melanogaster

AU - Antosyuk, O. N.

AU - Bolotnik, E. V.

AU - Obvitsev, D. V.

N1 - The research funding from the Ministry of Science and Higher Education of the Russian Federation (Ural Federal University Program of Development within the Priority-2030 Program) is gratefully acknowledged.

PY - 2023

Y1 - 2023

N2 - The protective properties of the extract of Monarda fistulosa var. menthifolia were tested when used together with the antitumor drug etoposide on Drosophila melanogaster. 1%, 10% extracts of M. fistulosa var. menthifolia were tested, separately and together with etoposide at 800 µg kg−1 of nutrient medium. The genotoxic effect was determined using the SMART method. Cytotoxicity was determined by assessing regulated cell death (RCD). While the extract of M. fistulosa var. menthifolia at 1% (20 mg mL−1) did not show genotoxicity, and had antigenotoxicity, reducing the genetic activity of the anticancer drug etoposide, at 10% (200 mg mL−1) it showed geno- and cytotoxicity. © 2023 Taylor & Francis Group, LLC.v

AB - The protective properties of the extract of Monarda fistulosa var. menthifolia were tested when used together with the antitumor drug etoposide on Drosophila melanogaster. 1%, 10% extracts of M. fistulosa var. menthifolia were tested, separately and together with etoposide at 800 µg kg−1 of nutrient medium. The genotoxic effect was determined using the SMART method. Cytotoxicity was determined by assessing regulated cell death (RCD). While the extract of M. fistulosa var. menthifolia at 1% (20 mg mL−1) did not show genotoxicity, and had antigenotoxicity, reducing the genetic activity of the anticancer drug etoposide, at 10% (200 mg mL−1) it showed geno- and cytotoxicity. © 2023 Taylor & Francis Group, LLC.v

UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85158127522

U2 - 10.1080/10496475.2023.2180698

DO - 10.1080/10496475.2023.2180698

M3 - Article

VL - 29

SP - 308

EP - 317

JO - Journal of Herbs, Spices & Medicinal Plants

JF - Journal of Herbs, Spices & Medicinal Plants

SN - 1049-6475

IS - 3

ER -

ID: 40786095