Результаты исследований: Вклад в журнал › Материалы конференции › Рецензирование
Результаты исследований: Вклад в журнал › Материалы конференции › Рецензирование
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TY - JOUR
T1 - Synthesis and study of the antifungal activity of 1-(2-cyanophenyl)-3-heterylureas
AU - Dunaeva, Kristina
AU - Baratova, Daria
AU - Kalinina, Tatiana
AU - Glukhareva, Tatiana
N1 - This research was supported by the Russian Science Foundation and Government of Sverdlovsk region, Joint Grant No 22-26-20124, https://rscf.ru/en/project/22-26-20124/ (accessed on 30 October 2023).
PY - 2024/1/1
Y1 - 2024/1/1
N2 - In the treatment and prevention of fungal infections of plants, along with fungicides, inducers of systemic plant resistance, also called elicitors, have become particularly important in recent years. In this work, a method was developed for the synthesis of new 3,4-dichloroisothiazol-5-yl and 4-methyl-1,2,3-thiadiazol-5-yl ureas 1,2, containing a 2-cyanophenyl substituent, structurally similar to a known synthetic elicitors isotianil and tiadinil. The protective properties of the obtained compounds on cucumber and pepper leaves infected with B. cinerea, as well as their fungicidal properties against B. cinerea, were studied. It has been established that disubstituted ureas 1,2 exhibit very low fungicidal activity against this fungus, about 11%. At the same time, study on plant leaves showed that compound 2 effectively inhibited the development of gray mold on both cucumber and pepper leaves with an inhibition rate of more than 90%, which was similar to tiadinil. Compound 1 was effective only on cucumber leaves (96.50±0.01%). Isotianil in the experiment showed an average degree of protection - 62.48±1.04% on cucumber leaves and 56.50±1.29% on pepper leaves. © The Authors, published by EDP Sciences. This is an open access article distributed under the terms of the Creative Commons Attribution License 4.0 (https://creativecommons.org/licenses/by/4.0/).
AB - In the treatment and prevention of fungal infections of plants, along with fungicides, inducers of systemic plant resistance, also called elicitors, have become particularly important in recent years. In this work, a method was developed for the synthesis of new 3,4-dichloroisothiazol-5-yl and 4-methyl-1,2,3-thiadiazol-5-yl ureas 1,2, containing a 2-cyanophenyl substituent, structurally similar to a known synthetic elicitors isotianil and tiadinil. The protective properties of the obtained compounds on cucumber and pepper leaves infected with B. cinerea, as well as their fungicidal properties against B. cinerea, were studied. It has been established that disubstituted ureas 1,2 exhibit very low fungicidal activity against this fungus, about 11%. At the same time, study on plant leaves showed that compound 2 effectively inhibited the development of gray mold on both cucumber and pepper leaves with an inhibition rate of more than 90%, which was similar to tiadinil. Compound 1 was effective only on cucumber leaves (96.50±0.01%). Isotianil in the experiment showed an average degree of protection - 62.48±1.04% on cucumber leaves and 56.50±1.29% on pepper leaves. © The Authors, published by EDP Sciences. This is an open access article distributed under the terms of the Creative Commons Attribution License 4.0 (https://creativecommons.org/licenses/by/4.0/).
UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85183306472
U2 - 10.1051/e3sconf/202447403008
DO - 10.1051/e3sconf/202447403008
M3 - Conference article
VL - 474
JO - E3S Web of Conferences
JF - E3S Web of Conferences
SN - 2261-236X
M1 - 03008
T2 - 10th International Annual Conference on Industrial Technologies and Engineering, ICITE 2023
Y2 - 9 November 2023
ER -
ID: 52304021