Результаты исследований: Вклад в журнал › Обзорная статья › Рецензирование
Результаты исследований: Вклад в журнал › Обзорная статья › Рецензирование
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TY - JOUR
T1 - Poriferan chitin: 3D scaffolds from nano- to macroscale. A review
AU - Petrenko, Iaroslav
AU - Khrunyk, Yuliya
AU - Voronkina, Alona
AU - Kovalchuk, Valentine
AU - Fursov, Andriy
AU - Tsurkan, Dmitry
AU - Ivanenko, Viatcheslav N.
PY - 2020
Y1 - 2020
N2 - Modern scaffolding strategy with respect to chitin is based on the application of naturally prefabricated 3D chitinous scaffolds of both aquatical and terrestrial invertebrates origin, mostly in the form of decellularized matrices. The sources of such constructs should be renewable or represent biodegradable and non-toxic waste materials. Sponges (Porifera) have been recognized among the first multicellular organisms on Earth having survived for more than 500 million yearsdue to their ability to synthetize robust skeletons with uniquely developed microporous 3D architecture and protect themselves from predatory microorganisms through the production of diverse secondary metabolites with multi-target biological activities. In this study, we analysed the occurrence of naturally pre-designed 3D chitinous matrices reported in sponges on nano-, micro-and macro-scale levels for the first time. Special focus is dedicated to the practical applications of such unique constructs in biomedicine.
AB - Modern scaffolding strategy with respect to chitin is based on the application of naturally prefabricated 3D chitinous scaffolds of both aquatical and terrestrial invertebrates origin, mostly in the form of decellularized matrices. The sources of such constructs should be renewable or represent biodegradable and non-toxic waste materials. Sponges (Porifera) have been recognized among the first multicellular organisms on Earth having survived for more than 500 million yearsdue to their ability to synthetize robust skeletons with uniquely developed microporous 3D architecture and protect themselves from predatory microorganisms through the production of diverse secondary metabolites with multi-target biological activities. In this study, we analysed the occurrence of naturally pre-designed 3D chitinous matrices reported in sponges on nano-, micro-and macro-scale levels for the first time. Special focus is dedicated to the practical applications of such unique constructs in biomedicine.
UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85088485181
U2 - 10.33263/LIANBS92.10041014
DO - 10.33263/LIANBS92.10041014
M3 - Review article
VL - 9
SP - 1004
EP - 1014
JO - Letters in Applied NanoBioScience
JF - Letters in Applied NanoBioScience
SN - 2284-6808
IS - 2
ER -
ID: 37136071