The article analyzes the typical design and materials of thermal insulation of cryogenic pipelines, compares them on the basis of thermal conductivity, and considers the key differences in the regulatory and technical documents of the Russian Federation, the People's Republic of China and the European Union, which should be taken into account in the design of thermal insulation of pipelines at low-tonnage LNG facilities. A number of regulatory requirements in the Russian Federation restrict the use of commonly used materials such as polyisocyanurate and pouleorethane foam without the development of a safety case or the use of additional compensating measures. Thermal insulation structures based on aerogels or foam glass are acceptable, but have a number of shortcomings.