Результаты исследований: Вклад в журнал › Статья › Рецензирование
Результаты исследований: Вклад в журнал › Статья › Рецензирование
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TY - JOUR
T1 - Noise-induced structural transformations of oscillatory modes in calcium dynamics
AU - Ryashko, Lev
AU - Bashkirtseva, Irina
N1 - The work was supported by Russian Science Foundation (N 21-11-00062).
PY - 2023
Y1 - 2023
N2 - The problem of analyzing the internal mechanisms of structural transformations of non-equilibrium regimes in multi-component biological systems with random fluctuations is considered. Based on the Li–Rinzel model, we study how parametric noise deforms calcium oscillations, which play a key role in cellular processes. The conditions under which random forcing generates or suppresses spiking calcium oscillations are discussed. Parametric analysis of such stochastic transformations of calcium relaxation self-oscillations is carried out using statistics extracted from direct modeling and a new theoretical approach based on the method of confidence domains. © 2023, The Author(s), under exclusive licence to EDP Sciences, Springer-Verlag GmbH Germany, part of Springer Nature.
AB - The problem of analyzing the internal mechanisms of structural transformations of non-equilibrium regimes in multi-component biological systems with random fluctuations is considered. Based on the Li–Rinzel model, we study how parametric noise deforms calcium oscillations, which play a key role in cellular processes. The conditions under which random forcing generates or suppresses spiking calcium oscillations are discussed. Parametric analysis of such stochastic transformations of calcium relaxation self-oscillations is carried out using statistics extracted from direct modeling and a new theoretical approach based on the method of confidence domains. © 2023, The Author(s), under exclusive licence to EDP Sciences, Springer-Verlag GmbH Germany, part of Springer Nature.
UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85152663424
UR - https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=tsmetrics&SrcApp=tsm_test&DestApp=WOS_CPL&DestLinkType=FullRecord&KeyUT=000970846000008
U2 - 10.1140/epjs/s11734-023-00827-3
DO - 10.1140/epjs/s11734-023-00827-3
M3 - Article
VL - 232
SP - 1253
EP - 1259
JO - European Physical Journal: Special Topics
JF - European Physical Journal: Special Topics
SN - 1951-6355
IS - 8
ER -
ID: 41555102