Aggregation and disaggregation processes of lipid vesicles in water suspension were studied by computer simulation and laser backscattering techniques. Diffusion-limited aggregation algorithm of simulation model was enhanced to reversible cluster growth. It was estimated that morphological structure of clusters is controlled by the ratio of secondary minimum depth of vesicles interaction potential and their kinetics energy. Shear flow in Couette chamber made it possible to induce aggregation/disaggregation of vesicles under the different values of their kinetic energy due to shear flow ratio shift. Characteristic times of stasis and shear flow induced aggregation kinetics were determined by laser backscattering. Computer simulation is in good agreement with experimental data.