DOI

The present work is devoted to the electrochemical reduction study of presumably biologically active 2-substituted quinoxaline derivatives. In this work, two new quinoxaline derivatives are presented. The electrochemical behavior of this compound in an aprotic medium and while its protonating was investigated via a voltammetric method. Using computational methods, the localization of the reduction centres depending on the compound’s structure was determined. The EPR spectra data obtained by electrochemical generation reduction product proved that the studied quinoxaline’s electroconversion occurs with radical anion formation. The linear correlation between the reduction potential of studied compounds and energy of their affinity to the electron was found (R2 = 0.933). This confirms the single reduction mechanism of radical nature for the entire series of studied 2-substituted quinoxaline derivatives. Based on that, the electron-accepting ability of these compounds was compared in order to evaluate their possible bioactivity and to select the most perspective ones among them for further research. © 2023 by CEE (Center of Excellence in Electrochemistry).
Язык оригиналаАнглийский
Страницы (с-по)184-197
Число страниц14
ЖурналAnalytical and Bioanalytical Electrochemistry
Том15
Номер выпуска3
DOI
СостояниеОпубликовано - 2023

    Предметные области ASJC Scopus

  • Analytical Chemistry
  • Electrochemistry

    Предметные области WoS

  • Электрохимия

ID: 37830900