Standard

Efficient one-pot synthesis of 3-(polyfluoroalkyl)pyrazol-4-amines. / Filyakova, Vera; Boltacheva, Nadezhda; Slepukhin, Pavel и др.
в: Chemistry of Heterocyclic Compounds, Том 59, № 8, 01.08.2023, стр. 546-553.

Результаты исследований: Вклад в журнал › Статья › Рецензирование

Harvard

Filyakova, V, Boltacheva, N, Slepukhin, P & Charushin, V 2023, 'Efficient one-pot synthesis of 3-(polyfluoroalkyl)pyrazol-4-amines', Chemistry of Heterocyclic Compounds, Том. 59, № 8, стр. 546-553. https://doi.org/10.1007/s10593-023-03232-9

APA

Filyakova, V., Boltacheva, N., Slepukhin, P., & Charushin, V. (2023). Efficient one-pot synthesis of 3-(polyfluoroalkyl)pyrazol-4-amines. Chemistry of Heterocyclic Compounds, 59(8), 546-553. https://doi.org/10.1007/s10593-023-03232-9

Vancouver

Filyakova V, Boltacheva N, Slepukhin P, Charushin V. Efficient one-pot synthesis of 3-(polyfluoroalkyl)pyrazol-4-amines. Chemistry of Heterocyclic Compounds. 2023 авг. 1;59(8):546-553. doi: 10.1007/s10593-023-03232-9

Author

Filyakova, Vera ; Boltacheva, Nadezhda ; Slepukhin, Pavel и др. / Efficient one-pot synthesis of 3-(polyfluoroalkyl)pyrazol-4-amines. в: Chemistry of Heterocyclic Compounds. 2023 ; Том 59, № 8. стр. 546-553.

BibTeX

@article{3d65c314c54e40c2959422c9ce252b95,
title = "Efficient one-pot synthesis of 3-(polyfluoroalkyl)pyrazol-4-amines",
abstract = "A simple convenient one-pot protocol for the synthesis of 5-alkyl/hetaryl-4-amino-3-(polyfluoroalkyl)pyrazoles (4-aminopyrazoles) has been suggested. The method is based on using readily available lithium 3-polyfluoroalkyl-1,3-diketonates and sodium nitrite as starting materials and hydrazine hydrate for cyclization into 4-nitroso-3-(polyfluoroalkyl)pyrazoles, followed by reduction of the latter into target products. Molecular structures of 5-methyl-, 5-(thiophen-2-yl)-, 5-(4-methylphenyl)-, and 5-(pyridin-2-yl)-substituted 3-trifluoromethyl-1H-pyrazol-4-amines have been established by X-ray analysis.",
author = "Vera Filyakova and Nadezhda Boltacheva and Pavel Slepukhin and Valery Charushin",
year = "2023",
month = aug,
day = "1",
doi = "10.1007/s10593-023-03232-9",
language = "English",
volume = "59",
pages = "546--553",
journal = "Chemistry of Heterocyclic Compounds",
issn = "0009-3122",
publisher = "Springer Verlag",
number = "8",

}

RIS

TY - JOUR

T1 - Efficient one-pot synthesis of 3-(polyfluoroalkyl)pyrazol-4-amines

AU - Filyakova, Vera

AU - Boltacheva, Nadezhda

AU - Slepukhin, Pavel

AU - Charushin, Valery

PY - 2023/8/1

Y1 - 2023/8/1

N2 - A simple convenient one-pot protocol for the synthesis of 5-alkyl/hetaryl-4-amino-3-(polyfluoroalkyl)pyrazoles (4-aminopyrazoles) has been suggested. The method is based on using readily available lithium 3-polyfluoroalkyl-1,3-diketonates and sodium nitrite as starting materials and hydrazine hydrate for cyclization into 4-nitroso-3-(polyfluoroalkyl)pyrazoles, followed by reduction of the latter into target products. Molecular structures of 5-methyl-, 5-(thiophen-2-yl)-, 5-(4-methylphenyl)-, and 5-(pyridin-2-yl)-substituted 3-trifluoromethyl-1H-pyrazol-4-amines have been established by X-ray analysis.

AB - A simple convenient one-pot protocol for the synthesis of 5-alkyl/hetaryl-4-amino-3-(polyfluoroalkyl)pyrazoles (4-aminopyrazoles) has been suggested. The method is based on using readily available lithium 3-polyfluoroalkyl-1,3-diketonates and sodium nitrite as starting materials and hydrazine hydrate for cyclization into 4-nitroso-3-(polyfluoroalkyl)pyrazoles, followed by reduction of the latter into target products. Molecular structures of 5-methyl-, 5-(thiophen-2-yl)-, 5-(4-methylphenyl)-, and 5-(pyridin-2-yl)-substituted 3-trifluoromethyl-1H-pyrazol-4-amines have been established by X-ray analysis.

UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85172985826

UR - https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=tsmetrics&SrcApp=tsm_test&DestApp=WOS_CPL&DestLinkType=FullRecord&KeyUT=001077359800004

U2 - 10.1007/s10593-023-03232-9

DO - 10.1007/s10593-023-03232-9

M3 - Article

VL - 59

SP - 546

EP - 553

JO - Chemistry of Heterocyclic Compounds

JF - Chemistry of Heterocyclic Compounds

SN - 0009-3122

IS - 8

ER -

ID: 46907949