One of the promising areas is the study of continuously changing and evolving in time discrete-continuous structures. The most complex systems of this type include ecosystems with dynamically changing set of spatial distributed active agents and passive objects constantly interacting with each other. The main goals of researching such systems are ecosystems development forecast, as well as to analyze the results of various types of external influences. Special requirements for the languages and modeling tools of such systems specified by a wide variety of types of objects and subjects of social systems, their internal processes, as well as ways of interaction between subjects. This study conducted to comperative analysis of the MATLAB.Stateflow/Simulink and AnyDynamics software environments according to the possibilities of their usage for models constructing of social spatial distributed systems. The ability to define a model of interacting hybrid automaton based on state diagrams with objects states and continuous processes in each of the states is considered as mandatory requirements for tools. The package comparison is based on the extended requirements of the CSSL standard. By the majority of analyzed parameters, such as: the possibility of the DAE index reduction, structural dynamics, multicomponent assembly of the model, various classes of agents and objects initial generation in large sets, simple modeling of communication processes between agents, the use of Russian-language terms, and the license cost, is determined that AnyDynamics surpasses the MATLAB Stateflow/Simulink packages.