The heat transfer from a single sphere suspended in a cylindrical channel with finely dispersed air-water (aerosol) flow is experimentally studied. Under stationary heating conditions, the values of the heat-transfer coefficients are obtained as dependent on the Reynolds number and the water mist rate. A physical model of heat transfer from the sphere surface with water mist-air flow is proposed, which allows evaluating the processes proceeding at the various stages of droplet evaporation in the flow near a heated surface and formation of a water film on the surface itself. The relative mass of the droplet moisture deposited on the sphere surface is estimated depending on the water mist rate and Reynolds number of the flow. A criterial equation is obtained that generalizes the experimental data in the form of the dependence of Nusselt number on the regime parameters of Reynolds, Weber, and the water-to-steam phase transition parameter is obtained.