The paper determines the conditions of online learners’ social adjustment in a multicultural environment. The issue of finding an approach that would ensure adaptability and stability of personality in an entropic environment, as well as successful development and interaction in a multicultural space, gains newfound relevance. 177 students of the Yelabuga Institute of Kazan Federal University took part in the study. The developed course was delivered to the experimental group. The Student Adaptation to College Questionnaire was used to collect data. Improvements in the experimental group’s social adjustment indicators, derived in the course of statistical analysis of data, suggest the effectiveness of the methods used. Experimental validity of the effectiveness reveals the prospects for further research and implementation of the technology in the universities’ educational systems. The obtained data and coordination of conclusions with available research stipulate the need to study the issue of creation of unified competence and online training of instructors for a multicultural education system. The current article is quite relevant for further research on students’ adaptation in a multicultural environment, which is appropriate in a rapidly globalizing world, where everyone today needs a sufficient level of intercultural competence. © 2023 Fundacion Infancia y Aprendizaje.