Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - New synthesis of 1,4-benzothiazepin-5-ones
AU - Mironov, M. A.
AU - Ivantsova, M. N.
AU - Tokareva, M. I.
AU - Mokrushin, V. S.
PY - 2004/6/1
Y1 - 2004/6/1
N2 - A new convenient method for the synthesis of 1,4 -benzothiazepin-5-ones by a one-pot procedure including condensation of thiosalicylic acid with chloroacetone and the reaction of the resulting 2-(acetoxythio)benzoic acid without isolation with primary amines and isocyanides is proposed. This method can be used for the combinatorial search of compounds with biological activities in the 1,4-benzothiazepine series.
AB - A new convenient method for the synthesis of 1,4 -benzothiazepin-5-ones by a one-pot procedure including condensation of thiosalicylic acid with chloroacetone and the reaction of the resulting 2-(acetoxythio)benzoic acid without isolation with primary amines and isocyanides is proposed. This method can be used for the combinatorial search of compounds with biological activities in the 1,4-benzothiazepine series.
UR - https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=tsmetrics&SrcApp=tsm_test&DestApp=WOS_CPL&DestLinkType=FullRecord&KeyUT=000224147800013
UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=4644345077
U2 - 10.1023/B:RUCB.0000042278.14695.b3
DO - 10.1023/B:RUCB.0000042278.14695.b3
M3 - Article
VL - 53
SP - 1232
EP - 1236
JO - Russian Chemical Bulletin
JF - Russian Chemical Bulletin
SN - 1066-5285
IS - 6
ER -
ID: 43815348