[Figure not available: see fulltext.][Figure not available: see fulltext.]In this minireview, we cover new methods for the synthesis of indolo[2,3-b]quinoxaline derivatives that have been published over the previous decade. The majority of the approaches reported in the literature rely on transition-metal-catalyzed cross-coupling reactions and direct С–Н functionalization, as well as intramolecular oxidative cyclodehydrogenation processes (SNH reactions). [Figure not available: see fulltext.] © 2023, Springer Science+Business Media, LLC, part of Springer Nature.