The article provides systematization and comparative analysis of data for structural and phase states and set of physical and mechanical properties formed in deformable tube semi-finished products. Analysis includes various stages of obtaining hot-extruded tubes of titanium alloys PT-1M, PT-7M, Ti–3Al–2.5V. The relationship between characteristics of macro-, microstructure, parameters of the phases formed with spread of hardness values in the original hot-forged tube billets is established. Physical simulation of hot deformation processes of alloys with varying temperature and upsetting deformation rate is conducted. Recommendations for extrusion temperature ranges for each alloy are proposed. These recommendations are based on energy-power parameters of industrial equipment used and restrictions imposed by the structure. Evolution of the structure and change in hardness during expansion of a tube billet made from the alloys investigated are considered. Results of computer simulations of energy-power parameters of tube extrusion and their comparison with industrial experiment data are presented. Features of the structure, texture and their relationship with tube mechanical properties are established.