Iron and Molybdenum Content in the Immune-Privileged Organs of Rats upon the Administration of Nanocluster Porous Spherical Keplerate-Type Polyoxometalate {Mo72Fe30}

Standard

Iron and Molybdenum Content in the Immune-Privileged Organs of Rats upon the Administration of Nanocluster Porous Spherical Keplerate-Type Polyoxometalate {Mo72Fe30}. / Ostroushko, A. A.; Gette, I. F.; Danilova, I. G. et al.
In: Nanobiotechnology Reports, Vol. 18, No. 6, 01.12.2023, p. 945-951.

Research output: Contribution to journal › Article › peer-review

BibTeX

@article{bde119e152d14f658e4aca0ce5f1d7ff,

title = "Iron and Molybdenum Content in the Immune-Privileged Organs of Rats upon the Administration of Nanocluster Porous Spherical Keplerate-Type Polyoxometalate {Mo72Fe30}",

abstract = "Studies of the concentration of iron and molybdenum in the immune-privileged organs of rats without a pathology and after simulating posthemorrhagic anemia, which received intramuscular injections of Keplerate-type nanocluster porous spherical polyoxometalate (POM) {Mo72Fe30}, are conducted. The blood–testis barrier is the most resistant to the penetration of the components of POM, the blood–brain and blood–ocular barriers possess a lower resistance (accumulation of iron after 30 injections of POM), and the blood–thymus barrier is the least resistant. The borrowing of iron from immune-privileged organs such as the brain, eyeballs, and thymus occurs in the early stages (1 to 7 days) of posthemorrhagic anemia. Posthemorrhagic anemia decreases the resistance of the blood–brain barrier and is accompanied by the excessive accumulation of iron after seven injections of POM.",

author = "Ostroushko, {A. A.} and Gette, {I. F.} and Danilova, {I. G.} and Medvedeva, {S. Yu.} and Koveza, {E. V.} and Andreeva, {M. A.} and Morozova, {M. V.} and Tonkushina, {M. O.}",

note = "This work was partially financially supported within the framework of a State Task from the Ministry of Science and Higher Education of the Russian Federation (project no. 123031300049-8).",

year = "2023",

month = dec,

day = "1",

doi = "10.1134/S2635167623601079",

language = "English",

volume = "18",

pages = "945--951",

journal = "Nanobiotechnology Reports",

issn = "2635-1676",

publisher = "Pleiades Publishing",

number = "6",

}

RIS

TY - JOUR

T1 - Iron and Molybdenum Content in the Immune-Privileged Organs of Rats upon the Administration of Nanocluster Porous Spherical Keplerate-Type Polyoxometalate {Mo72Fe30}

AU - Ostroushko, A. A.

AU - Gette, I. F.

AU - Danilova, I. G.

AU - Medvedeva, S. Yu.

AU - Koveza, E. V.

AU - Andreeva, M. A.

AU - Morozova, M. V.

AU - Tonkushina, M. O.

N1 - This work was partially financially supported within the framework of a State Task from the Ministry of Science and Higher Education of the Russian Federation (project no. 123031300049-8).

PY - 2023/12/1

Y1 - 2023/12/1

N2 - Studies of the concentration of iron and molybdenum in the immune-privileged organs of rats without a pathology and after simulating posthemorrhagic anemia, which received intramuscular injections of Keplerate-type nanocluster porous spherical polyoxometalate (POM) {Mo72Fe30}, are conducted. The blood–testis barrier is the most resistant to the penetration of the components of POM, the blood–brain and blood–ocular barriers possess a lower resistance (accumulation of iron after 30 injections of POM), and the blood–thymus barrier is the least resistant. The borrowing of iron from immune-privileged organs such as the brain, eyeballs, and thymus occurs in the early stages (1 to 7 days) of posthemorrhagic anemia. Posthemorrhagic anemia decreases the resistance of the blood–brain barrier and is accompanied by the excessive accumulation of iron after seven injections of POM.

AB - Studies of the concentration of iron and molybdenum in the immune-privileged organs of rats without a pathology and after simulating posthemorrhagic anemia, which received intramuscular injections of Keplerate-type nanocluster porous spherical polyoxometalate (POM) {Mo72Fe30}, are conducted. The blood–testis barrier is the most resistant to the penetration of the components of POM, the blood–brain and blood–ocular barriers possess a lower resistance (accumulation of iron after 30 injections of POM), and the blood–thymus barrier is the least resistant. The borrowing of iron from immune-privileged organs such as the brain, eyeballs, and thymus occurs in the early stages (1 to 7 days) of posthemorrhagic anemia. Posthemorrhagic anemia decreases the resistance of the blood–brain barrier and is accompanied by the excessive accumulation of iron after seven injections of POM.

UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85184838048

UR - https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=tsmetrics&SrcApp=tsm_test&DestApp=WOS_CPL&DestLinkType=FullRecord&KeyUT=001160071500001

U2 - 10.1134/S2635167623601079

DO - 10.1134/S2635167623601079

M3 - Article

VL - 18

SP - 945

EP - 951

JO - Nanobiotechnology Reports

JF - Nanobiotechnology Reports

SN - 2635-1676

IS - 6

ER -

ID: 52960242