Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Interaction of 2-Amino-(4-aryl)-Substituted Thia- and Oxazoles with 5-Cyano-1,2,4-triazines
AU - Krinochkin, A.
AU - Rammohan, A.
AU - Shtaitz, Ya.
AU - Kopchuk, D.
AU - Ladin, E.
AU - Sharafieva, E.
AU - Taniya, O.
AU - Zyryanov, G.
AU - Matern, A.
AU - Chupakhin, O.
N1 - This work was supported by the Council for Grants of the President of the Russian Federation (Grant no. MK-320.2021.1.3).
PY - 2023/1/1
Y1 - 2023/1/1
N2 - An interaction of 6-aryl-1,2,4-triazine-5-carbonitriles with 2‑amino-4-aryl-substituted thiazoles and oxazoles has been studied. The difference in the reactivity of these aminoheterocycles depending on the presence of an oxygen or a sulfur atom in their composition has been demonstrated. Previously, the 4-aryl-3-hydroxy-2,2′-bipyridines were obtained as products of aza-Diels−Alder reaction between 6-aryl-3-(2-pyridyl)-1,2,4-triazine-5-carbonitriles and 2-amino-4-aryloxazoles. It was shown that the reaction of 6-aryl-1,2,4-triazine-5-carbonitriles with 2-aminothiazoles led to the products of ipso-substitution of cyano group. The aza-Diels−Alder reaction of these compounds with 2,5-norbornadiene gave (2,2′-bi)pyridines with the 2-aminothiazolyl at alpha-position.
AB - An interaction of 6-aryl-1,2,4-triazine-5-carbonitriles with 2‑amino-4-aryl-substituted thiazoles and oxazoles has been studied. The difference in the reactivity of these aminoheterocycles depending on the presence of an oxygen or a sulfur atom in their composition has been demonstrated. Previously, the 4-aryl-3-hydroxy-2,2′-bipyridines were obtained as products of aza-Diels−Alder reaction between 6-aryl-3-(2-pyridyl)-1,2,4-triazine-5-carbonitriles and 2-amino-4-aryloxazoles. It was shown that the reaction of 6-aryl-1,2,4-triazine-5-carbonitriles with 2-aminothiazoles led to the products of ipso-substitution of cyano group. The aza-Diels−Alder reaction of these compounds with 2,5-norbornadiene gave (2,2′-bi)pyridines with the 2-aminothiazolyl at alpha-position.
UR - https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=tsmetrics&SrcApp=tsm_test&DestApp=WOS_CPL&DestLinkType=FullRecord&KeyUT=000994243700005
UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=85160030930
U2 - 10.1134/S0012500823600153
DO - 10.1134/S0012500823600153
M3 - Article
VL - 508
SP - 28
EP - 31
JO - Doklady Chemistry
JF - Doklady Chemistry
SN - 0012-5008
IS - 1
ER -
ID: 40049893