Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Acceleration of the Passerini reaction in the presence of nucleophilic additives
AU - Mironov, Maxim A.
AU - Ivantsova, Maria N.
AU - Tokareva, Maria I.
AU - Mokrushin, Vladimir S.
N1 - This work was supported in part by CRDF (REC-005).
PY - 2005/6/1
Y1 - 2005/6/1
N2 - An accelerating effect of nucleophilic additives was revealed for the Passerini multi-component reaction. The influence of aqueous solutions on the reaction rate was studied in detail and the direct involvement of water in the bond-making step was attributed as the basis of an accelerating effect. Other nucleophiles were tested as alternatives to water; as a result N-hydroxysuccinimide is proposed as an accelerant of the Passerini reaction.
AB - An accelerating effect of nucleophilic additives was revealed for the Passerini multi-component reaction. The influence of aqueous solutions on the reaction rate was studied in detail and the direct involvement of water in the bond-making step was attributed as the basis of an accelerating effect. Other nucleophiles were tested as alternatives to water; as a result N-hydroxysuccinimide is proposed as an accelerant of the Passerini reaction.
UR - https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=tsmetrics&SrcApp=tsm_test&DestApp=WOS_CPL&DestLinkType=FullRecord&KeyUT=000229484600002
UR - http://www.scopus.com/inward/record.url?partnerID=8YFLogxK&scp=18844363719
U2 - 10.1016/j.tetlet.2005.04.050
DO - 10.1016/j.tetlet.2005.04.050
M3 - Article
VL - 46
SP - 3957
EP - 3960
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 23
ER -
ID: 39762123