The variability of complexes of related elements of morphological characteristics and the content of tannins in plants of Betonica officinalis L. on the territory of the Southern and Middle Urals was analyzed. It has been established that the variability of morphological and biochemical characteristics of Betonica officinalis L. has a coordinated zonal character in the Southern and Middle Urals. It is shown that, based on the analysis of complexes of related elements of flower characteristics in Betonica officinalis L., the content of tannins can be predicted in natural populations.