The microstructure and properties of the hot-extruded Ti-3Al-2.5V pipe subjected to vacuum annealing are studied using methods of macro-, micro-, X-ray analyses, tensile and Vickers hardness tests. It is shown that recrystallization of the α-phase and formation of a more equilibrium (α+β)-state change of occur in the microstructure, during vacuum annealing, in comparison with as hot-extruded. This change are resalted in chemical composition, volume fraction of phases. It is revealed that the recrystallization processes throughwall section play the certain role in formation of the texture state in several/various sections (outer surface, 1/2 wall thickness, inner surface of the pipe). It is noted that vacuum annealing contributes to reduction of hardness spread in the section of the pipes and to formation of the combination of mechanical properties with high plasticity and moderate strength.