The paper proposes to supplement the monitoring of strain uniformity over the cross-section of extruded aluminum alloy bars, based on the macro- and microstructure in the central part, at ½ radius, and in the surface zone in several cross-sections along the length of press products, with microindentation of these sections. For this purpose, the microstructure, the loading diagram, and the pattern of the distribution of micromechanical properties across the cross-section of extruded bars made of the AD33 and D16 aluminum alloys are comparatively analyzed. These alloys differ in that in one alloy, AD33, the alloying elements strengthen the aluminum-based solid solution without forming independent phases, and in the other, D16, they form strengthening intermetallic compounds Al2CuMg. The microhardness of the AD33 alloy is ~55 HV 0.1, that of the D16 alloy being 120 HV 0.1. The alloys differ in the distribution of micromechanical properties over both the transverse and longitudinal sections of the extruded bars. It has been found that maximum homogeneity is characteristic of the central part of the rods made of both alloys. The microindentation data correlate with the changes in the microstructure and the results of assessing the distribution of microstrains in the crystal lattice of an aluminum-based solid solution over the cross-section of extruded products by EBSD using recrystallization maps. This makes it possible to recommend the microindentation method for assessing the distribution of strains over the cross-section of extruded aluminum alloy bars.