The article reviews the book Maltsev A. A. Global Techno-Economic Modern Challenges in Current Epoch: Ricks And Possibilities for Ural Industry. - Yekaterinburg : Alfa-Print, 2022 as well as his articles on sanctions and digital transformation of the industry. The authors, based on an integrated approach, more deeply revealed the essence of the three main challenges (the fourth technological revolution, reformatting of cross-border value chains and energy transition to a carbon-free economy) in the context of the country's industrial development; clarified the patterns of world economic interaction formed under the influence of these challenges; generalized both obstacles to the successful industrial development of Russia, and proposals for their elimination. The specificity of the article is that these three challenges are considered in interaction with each other, for example, the impact of the change of technological structure on the value chains and the "green" economy at the same time.