The blood pressure is important becausethe high blood pressure indicates higher riskof health problem in the future. In this paper, we investigate the relationship of ageand blood cholesterol on blood pressure. Thedata for this research was collected by «Missan Center For Cardiac Disease & Surgery» inAlamara (in Iraq). We used Matlab softwarefor simulation. The linear regression analyses showed that cholesterol and age are directly related to systolic blood pressure forcollected data