The problem of estimation and management of competitive ability of big integrated structures that define the situation in international and home markets is extremely up-to-date nowadays. The article offers a new methodic approach to estimation and management of competitive ability of manufacturing complex. The method includes two big blocks: a) block of estimation of competitive ability status of manufacturing complex on the reporting date, and b) block of optimization of development investment portfolio of manufacturing complex in terms of improvement of competitive ability. Finally, test calculation according to the offered method on the example of one Russian machinery complex is given.