The monograph was written by a team of authors based on the results of the interregional conference "The possibilities of combining natural and artificial intelligence in educational systems", as well as on the basis of regular meetings within the framework of the virtual laboratory for the study of artificial intelligence and robotics. The discussion was held in a format combined with a meeting of the Southern Branch of the Interregional Public Organization "Academy of Informatization of Education" (UO AIO), which has already turned 20 years old. The main objective of the conference was to analyze the possibilities of interaction between natural and artificial intelligence in educational systems of various levels, the issues of the use of modern information technologies, software, artificial intelligence, digitalization in educational organizations in the implementation of educational activities and the educational process, robotic technologies in education, etc. were considered. The proposed materials may be useful to specialists of the Department of the education system of Russia and its regions, employees of federal and regional authorities and management, as well as regional associations of academic mobility.