The article presents a phenomenological approach to the description of the processes of self-organization when transferring nanocluster compounds ( buckyballs ) drug in the skin. As part of setting goals with the aggravation of Samara considered nonlinear parabolic equation for the concentration values ​​of buckyballs in the excited state with medication. Defined local expressions for the thermodynamic characteristics - chemical potential, the entropy production rate of change of entropy and free energy. Thermodynamic characteristics allow a self-organization in which there is a dissolution or «sticking» buckyballs, which is unfavorable in drug delivery. Also consider the two-stream model, which takes into account the external electric field imposed on a person's skin for better penetration into the skin and transfer of buckyballs drugs.