Standardization of the process of teaching chemistry dictates the need to develop the students' science literacy. This task can be implemented in the aspect of students' ability to transfer their knowledge and skills developed on typical tasks to a new, unfamiliar situation. The article considers an example of knowledge transfer in the studying the topic “Hydrolysis”. The need for the development of functional natural science literacy in school students is analyzed, which helps to improve the efficiency of transferring the acquired knowledge. It is shown that natural science literacy can be taught not only at school, but also at multidisciplinary preparation courses for the Unified State Examination. The percentage of students who received the minimum scores is approximately the same among all analyzed groups. Graduates of multidisciplinary courses do not have marks below the minimum score, but among them there is a higher percentage of students who receive an average score.