The article provides results of research into the impact of psychosomatic factors on successful conception in patients with idiopathic infertility who undergo treatment in the department of infertile marriage and ART of the Ural Research Institute of Maternity and Child Care. Infertility-related psychological targets and their correction by imaginative psychosomatic psychotherapeutic techniques can be a way to provide a solution to the infertility problem. A method to reduce the effect of distress hormones on the target reproductive function body organs was developed and tested. This method is rooted in the knowledge of neuroendocrine regulation of reproductive processes. The psychotherapeutic correction was based on the approaches of emotional-figurative therapy as a way to reduce the extremeness of living conditions while undergoing infertility treatment. Psychodynamic indicators of socio-psychological maladaptation, volitional tension, behavior constructiveness in distress situations, psychovegetative coefficient of ergicity were selected as the effectiveness criteria. © 2024, Moscow State University of Psychology and Education. All rights reserved.