The principal possibility of the transport of polyoxometalates Mo72Fe30 with the keplerate structure through the skin of animals (rats) was shown; the effectiveness of such transport is increasing under conditions of application of an electric field (electrophoresis). Experiments were carried out on isolated skin membrane and directly on experimental animals. The optimal operating modes of electrophoresis were selected and found no change in biochemical parameters used in the clinical laboratory to assess the functional state of the heart, liver, kidney and pancreas, after the action of the polyoxometallate in animals under experimental conditions.