FIELD: medicine.
SUBSTANCE: producing paracetamol involves the catalytic hydrogenation of p-nitrosophenol with Pd/C or Ni-Re catalysts at 20-70°C in a combination with acetylation in aqueous ethanol or aqueous isopropanol in the presence of acetic anhydride.
EFFECT: advanced method for producing p-acetylaminophenol using inexpensive solvents and ensuring a high product yield.
Translated title of the contributionMETHOD FOR PRODUCING PARACETAMOL: patent of invention
Original languageRussian
Patent number2574733
IPCC07C 233/25,C07C 231/10
Filing date26/12/2014
Publication statusPublished - 10 Feb 2016

ID: 10293005